Pharmacology (Revised Scheme) April 2002, Paper 1

1. Classify the antiarrhytmic drugs. Discuss the cardiovascular actions of Verapamil. Mention its therapeutic uses, adverse effects and contraindications.
2. Define the term BIOAVAILABILITY of drugs. Discuss the factor influencing the drug absorption and bioavailability of drug by oral route

3. Transdermal administration of drug.
4. Treatment of acute barbiturate poisoning.
5. Genetic factors influencing drug metabolism.
6. Drugs used for migraine prophylaxis.
7. Adverse effects of Phenytoin.
8. Therapeutic uses of digoxin.
9. Atropine substitutes.
10. Non sedating H1 blockers.
11. Mast cell stabilizers.
12. Therapeutic uses of anticholinesterase agents.

13. L-dopa is not useful in the treatment of drug induced Parkinsonism.
14. Propranolol is contraindicated in asthmatics.
15. Adrenaline is the drug of choice in anaphylactic shock
16. Thiazides are contraindicated in patients with diabetes mellitus.
17. Folic acid alone is contraindicated in patients with pernicious anemia.
18. Aspirin is used in the secondary prophylaxis of myocardial infarction.
19. Clonidine should not be withdrawn suddenly in hypertensive patients.
20. Rationale for using methadone in the management of morphine dependence.
21. Advantages of sublingual route.
22. Advantages of Fluoxetine over Imipramine.
23. Subcutaneous route is not preferred in the presence of shock.
24. Rationale for using vasodilators in cardiac failure.
25. Lignocaine is not effective in supraventricular arrhythmias.
26. Iron sorbitol citric acid is not suitable for IV administration.
27. Hydroxycobalamin is preferred to cyanocobalamin for long term administration.
28. Diazepam is less effective by IM route.

Question Paper Submitted by:
2003-04 Batch, BMC.


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