Pharmacology (Revised Scheme) Oct 2000, Paper 1

1. Classify the drug used in treatment of epilepsy. Write the mechanism of action and adverse effects of diphenylhydantion sodium.
2. Enumerate cardiac glycosides. Write the mechanism of action of digoxin. Mention its therapeutic uses.

3. Drug antagonism.
4. Merits and demerits of Halothane.
5. Prazosin.
6. Nimesulide.
7. Oral anticoagulants.
8. Enalapril.
9. Compare d-tubocurarine with succinyl choline.
10. Therapeutic uses and adverse effects of chlorothiazide.
11. Mechanism of action of local anaesthetics.
12. Prodrugs.

13. Two uses of pethidine.
14. Two factors influencing biotransformation of drugs.
15. Rationale for use of disulfiram in chronic alcoholism.
16. Name two atropine substitutes used in Parkinsonism.
17. Two therapeutic uses of carbamapezine.
18. Two contraindications of propranolol.
19. Explain why pentazocine is contraindicated in acute myocardial infarction.
20. Name two potassium sparing diuretics.
21. Name two newer antidepressants.
22. Atropine premedication is essential before ether anaesthesia.
23. Rationale for using lignocaine in ventricular arrhythmias.
24. Rationale for use of methadone in the treatment of opioid dependence.
25. Name two drugs contraindicated in CCF.
26. Define plasma half-life.
27. Name two plasma expanders
28. Folic acid alone not be used in pernicious anemia.

Question Paper Submitted by:
2003-04 Batch, BMC.


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