Pharmacology (Revised Scheme) Oct 2002, Paper 2

1. Enumerate the antitubercular drugs. Explain the mechanism of action and adverse effects of any two standard drugs. Describe the short course chemotherapy of tuberculosis.
2. Classify the drugs used in peptic ulcer. Explain the mechanism of action and therapeutic uses of proton pump inhibitors.

3. Betalactamase inhibitors.
4. Drugs used for HIV infection.
5. Treatment of lepra reactions.
6. Topical uses of glucocorticoids.
7. Second generation cephalosporins.
8. Insulin resistance.
9. Tocolyitc agents.
10. Sequential blockade.
11. Drugs used for resistant falciparum malaria.
12. Vinca alkaloids.

13. Rationale for using hyoscine in motion sickness.
14. Rationale for combining probenecid with penicillins.
15. Tetracyclines are contraindicated in children under 8 yrs and pregnant women.
16. Loperamide should not be used for infective diarrhoeas and dysenteries.
17. Estrogens containing contraceptive pills are not suitable for women above 35 yrs. Why?
18. Sulfonylurea are not effective in type I diabetes mellitus.
19. Only bactericidal drugs shall be used in the treatment of bacterial endocarditis.
20. Praziquental is preferred to niclosamide for the treatment of T.solium infestation.
21. Ergometrine is not suitable for induction of labour.
22. Use of vancomycin in the treatment of pseudomembranous colitis.
23. Glucocorticoids should not be stopped abruptly following long term administration.
24. Chloramphenicol is to be avoided in infants.
25. Amipicillin is preferred to benzyl penicillin for urinary tract infections.
26. Sulfonamides are less effective in the presence of pus.
27. Amino glycosides are not effective against intracellular pathogens.

Question Paper Submitted by:
2003-04 Batch, BMC.


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